Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the aberrant production of β2-glycoprotein I (B2GPI)-dependent antiphopholipid autoantibodies (aPL, including lupus anticoagulant, anticardiolipin antibodies, anti-B2GPI antibodies, etc.), and it manifests as arterial/venous thrombosis or obstetrical complications [1]. This evidence concerns the gene APOH and autoimmune disease.