The secretion of CCL6 and CCL23 by omental macrophages significantly increased the migration and colonisation of EOC cells via binding to CCR1 receptors on cancer cells and inducing the activation of the ERK1/2 and AKT pathways, where ERK activation is pivotal in cancer cell survival through the upregulation of antiapoptotic proteins and the inhibition of caspase activity [38,39]. This evidence concerns the gene MAPK3 and cancer.