A notable decrease in SOD (7.2 ± 1.2 U/mg, control group: 14.4 ± 1.5; p < 0.001) and GSH-Px (27.4 ± 4.6 U/g control group: 45.2 ± 5.3 U/g; p < 0.001) was observed in the BPH group. The gene discussed is SOD1; the disease is benign prostatic hyperplasia.