COL1A2 and Familial adenomatous polyposis: A cross-sectional study on 30 FAP patients bearing a germinal heterozygote mutation of the APC gene showed a significantly higher mean BMD at the lumbar spine, total hip, femoral neck and trochanter in FAP patients, with respect to age- and gender-matched healthy controls, in the presence of a balanced bone remodeling, as displayed by the mean concentrations of procollagen type I N-terminal propeptide and β-crosslaps being within the normal ranges [22].