CNMD and medullary thyroid gland carcinoma: A comparison of the gene expression profile between the specimens of Medullary Thyroid Carcinoma (MTC) from MEN2A and MEN2B patients showed that the malignant C cells of MEN2B MTCs expressed high levels of Chondromodulin 1 (CHM1) [33], a secreted glycoprotein known to be a regulator of cartilage and bone growth that is normally expressed in proliferating chondrocytes of the growth plates.