The genetically determined response to SNRIs—based on the analysis of the ABCB1 gene—showed a significant negative correlation with the CGI-BP-M overall score (p-value < 0.030) and the depression subscore (p-value < 0.026) at enrollment, indicating an association with lower scores in both domains of this scale (Table 3). This evidence concerns the gene ABCB1 and depressive symptom measurement.