Among the circRNAs differentially expressed in 2, 3, or all 4 of the brain studies, we identified six with known associations with AD pathology (Figure 7) [43], originating from genes DOCK1, NTRK2, DLG1, TRAPPC9, APC, and KIF1B. The circRNA coordinates, the number of studies in which they were differentially expressed, the number of circRNAs higher and lower in AD relative to control (direction of changes), and the links to AD pathobiology are listed. Here, APC is linked to Alzheimer disease.