VEGFA and fetal growth restriction: Nevertheless, since uterine arterial Ad.VEGF treatment appeared effective, a multinational, multidisciplinary collaboration to carry out a phase I/IIa clinical trial that aims to examine the safety and efficacy of maternal gene therapy as a treatment for severe early onset FGR has been put forth and known as the EVERREST Project (does vascular endothelial growth factor gene therapy safely improve outcome in severe early-onset fetal growth restriction) [76,77].