The BRCA2-MEILB2-BRME1 complex is required for the assembly of RAD51 and DMC1 at meiotic DSBs during spermatogenesis since deletion of any component in the complex diminishes RAD51 and DMC1 foci formation at recombination sites, causing impaired DSB repair and infertility [40,92,93,213]. Here, RAD51 is linked to Infertility.