Inherited myopathies are clinically and genetically heterogeneous diseases, with 13 clinical and/or histological entry diagnosis groups reported in the Gene Table of Neuromuscular Disorders, (http://www.musclegenetable.fr, accept on 9 July 2021) [1] More than 200 genes are implicated including the giant and complex titin (TTN) and nebulin (NEB) genes. The gene discussed is NEB; the disease is myopathy.