GRIN1 and Werner syndrome: Glutamate Ionotropic Receptor NMDA Type Subunit 1 (GRIN1) gene causes an EE (EOEE, WS) with background EEG deterioration, micro/macrocephaly, global DD, central visual impairment and a complex MD (oculogyric crises, choreoathethosis, chorea, dystonia, oculo-motor apraxia), with stereotypies (hand but also limbs) [25,64].