TNF and glaucoma: Still, a 2010 analysis of TNF-a concentrations in the aqueous humor of glaucoma patients found a significant association between TNF-a concentrations and glaucoma patients (mean concentration 15.9 ± 3.6 pg/mL, range 1.7–57.6 pg/mL) but was unable to find a relationship between IOP and TNF-a concentration (r = 0.163) [49].