As our male patients with contiguous gene deletions seemed to be affected by isolate choroideremia [11,26], we conclude that the genes located within the deleted genomic regions might have only indirect or subtle effects on the patients’ extra-ocular phenotype [43]; consequently, we can reasonably state that loss of ZNF711 is not associated with mental retardation, in our patients. Here, ZNF711 is linked to choroideremia.