SGK1 and epilepsy: The SGK1 S78 and S422 phosphorylation ratios in epilepsy rats were reduced to 0.48 (t(12) = 24.3, p < 0.001 vs. control animals, Student t-test) and 0.34 times (t(12) = 25.8, p < 0.001 vs. control animals, Student t-test) the control level (Figure 4E,F and Figure S2).