ABCG5 and hereditary disease: The protein encoded by ABCG5 (fold change 16.35) is one of the ATP-binding cassette (ABC) transporters superfamily members, involved in extra and intracellular membrane transport of different molecules and, in particular, of neutral sterol in hepatobiliary and transintestinal cholesterol excretion and its inactivating mutations cause a rare genetic disorder, Sitosterolemia [44].