The aim of this study was to evaluate the plasma levels of TRX1 and also MPO, chemerin and growth factors GDF-15, Ang-2, VEGF-A, FGF-2, FGF-21, MPP-1, -3, -9, and C-reactive protein (CRP) in acquired AS patients as well as to clarify the correlations of TXR1 and the plasma inflammatory biomarkers regarding AS severity. This evidence concerns the gene ANGPT2 and aortic valve stenosis.