ANGPTL4 and type 2 diabetes mellitus: The circulating levels of ANGPTL4 were increased in all the obese subgroups (MHO, MUO and T2D) compared to the lean subjects; of note, plasma ANGTPL4 was higher in the patients with T2D than in the other obese subgroups (MHO and MUO), whereas the difference between those with MHO and MUO was not statistically significant (Figure 1, right panel).