MASP2 and COVID-19: The detection of IgG and C1q in kidneys and liver is consistent with similar findings in the lung specimens and supports the conclusion that the classical pathway is the prevailing route of C activation, further amplified by the involvement of the alternative pathway, although the finding of MASP-2 deposits in 2 out of 9 COVID-19 renal biopsies by Pfister et al. [39] suggested the possible contribution of the lectin pathway.