CEACAM5 and metastatic neoplasm: According to the clinical risk score (CRS) for partial hepatectomy and the modified CRS for thermal ablation, well-known prognostic factors are size of the largest CRLM, number of CRLM and carcinoembryonic antigen (CEA) levels at the time of initial diagnosis of metastatic disease, node positive disease and a short (<12 months) disease-free interval between the primary tumor diagnosis and detection of CRLM [14,15,16,17].