GCG and early-onset autosomal dominant Alzheimer disease: A peptide discovered in Heloderma suspectum venom, consisting of 39 aminoacids with insulinotropic activity, called Exendin-4, is a short incretin-mimetic peptide with full agonist for the glucagon-like peptide 1 (GLP-1) receptor and produces insulinotropic effects, recently described with activity in Alzheimer disease stablish a solid precedent for T2DM therapies based on promising peptide compounds extracted from venomous animals [20,21,22,23].