For example, the lncRNA c-Myc inhibitory factor (MIF), found in B-cell lymphoma cells, is synthesized with the participation of c-Myc factor, but by binding miR-586 it activates the expression of ubiquitin ligase E3, which promotes the degradation of c-Myc factor. This evidence concerns the gene MYC and B-cell non-Hodgkin lymphoma.