FASLG and autoimmune polyendocrinopathy: Since 1–5% of people in the general population are aPL positive, current guidelines suggest that aPL status should be tested in patients considered at risk for APS, i.e., patients younger than 50 years, patients with unprovoked arterial or venous thrombosis, patients with thrombosis at an unusual site or patients with recurrent thrombotic events [24].