STAT3 and MALT lymphoma: Interestingly, MYD88 L265P mutants are constitutively active and capable of signaling to activate NF-κB, signal transducers and activators of transcription 3 (STAT3), and activator protein 1 (AP1) transcription factors, which was observed in gastric mucosa-associated lymphoid tissue (MALT) lymphomas [47].