NFKB1 and infection: The protein alpha-kinase 1 (ALPK1) and tumor necrosis factor receptor-associated factor (TRAF)-interacting protein with forkhead-associated domain (TIFA) are vital components in response to ADP-hep leading to the activation of classical NF-κB in pathogen infection including H. pylori-infected gastric epithelial cells [26,27].