ESR1 and triple-negative breast carcinoma: The subtypes are as follows: Luminal A (ER+ and/or PgR+, HER2-, Ki-67 < 14%), Luminal B (ER+ and/or PgR+, HER2-, Ki-67 high or ER+ and/or PgR+, HER2+, Ki-67 any), HER2-enriched (ER-, PgR-, HER2+) and triple negative breast carcinoma (TNBC) (ER-, PgR-, HER2-) [8].