ENPP2 and open-angle glaucoma: Recently, the aqueous autotaxin (ATX) and TGF-β levels were determined via enzymatic or multiplex immunoassay in the aqueous humor of a large cohort consisting of 281 subjects, including POAG (n = 97), SOAG (n = 48), PEXG (n = 48), and controls (n = 88).