Up: MMP-2 (2.1-fold PEXG vs. CT, 1.7-fold PEXG vs. POAG, 2.0-fold PES vs. CT), TIMP-2 (7.7-fold PEXG vs. CT, 3.0-fold POAG vs. CT, 6.0-fold PES vs. CT). Here, MMP2 is linked to open-angle glaucoma.