Moreover, in PEXG (n = 58) and PES (n = 47) patients the MDA and GSH levels were significantly higher than in controls (n = 134), while the activity of SOD and CAT were lower in both glaucoma and PES groups, with specific downregulation of nitric oxide concentration in PEXG, compared to PES and controls [155]. This evidence concerns the gene SOD1 and glaucoma.