Goyal et al., in a spectrophotometric targeted analysis in 2011 [68], observed a significant increase in SOD and GPx activity in both POAG (n = 30) and PACG (n = 30) aqueous humor compared to patients with cataracts (n = 30), while vitamins C and E were significantly lower in glaucoma subjects. This evidence concerns the gene SOD1 and open-angle glaucoma.