SOD1 and glaucoma: In a targeted analysis, the determination of serum oxidative degradation products in 160 glaucoma patients with different etiology and 31 controls demonstrated that total antioxidant capacity (TAC), SOD, and GPx were all found to be decreased, while MDA, serine, TF, and vitamins A and E were increased in glaucoma patients, revealing systemic lipid oxidation on the basis of glaucoma, and vitamin E as a potential neuroprotective agent [151].