Up: MMP-9 (7.1-fold POAG vs. CT, 5.7-fold NTG vs. CT, 1.2-fold POAG vs. NTG), MMP-2 (2.6-fold POAG vs. CT, 3.3-fold NTG vs. CT, 0.8-fold POAG vs. NTG), TIMP-1 (1.3-fold POAG vs. CT, 1.2-fold POAG vs. NTG), IP-10 (1.8-fold POAG vs. NTG), macrophage derived chemokine (MDC, 1.9-fold POAG vs. NTG), platelet derived growth factor-AA (PDGF-AA, 3.8-fold POAG vs. NTG), IL-1α (1.2-fold POAG vs. NTG), IL-8 (1.6-fold POAG vs. NTG), IL-7 (1.3-fold NTG vs. POAG), MCP-1 (1.3-fold NTG vs. POAG), TNF-β (1.3-fold NTG vs. POAG). The gene discussed is CXCL8; the disease is open-angle glaucoma.