DECs of the top 10 most abundant KEGG pathways are shown in Figure 2B. Six of the 10 pathways were detected at both 6 and 24 hpi, including cytokine-cytokine receptor interaction, viral protein interaction with cytokine and cytokine receptor, chemokine signaling pathway, Rheumatoid arthritis, IL–17 signaling pathway, and TNF signaling pathway. This evidence concerns the gene TNF and rheumatoid arthritis.