In addition to their use in diagnostics, these biomolecules are also useful in the treatment of conditions such as, arthritis, cancer, autoimmune diseases, Wilson disease, Alzheimer’s disease, fatty liver disease, and BRAF-positive cancers, a wide variety of infections, oxidative damage of many organs, vascular leak syndrome, neurodermatitis, bleeding, and wounds, as well as the prevention of cancer, liver cirrhosis, neurological tissue damage, skin conditions, diabetes, coronary heart disease, and osteoporosis. Here, BRAF is linked to early-onset autosomal dominant Alzheimer disease.