The identification of CYCS, VEGFA, IL6, UQCRC1, UQCRFS1, COX5B, ACKR3/CXCR7, and FYN as pro-tumorigenic nodes designates them as the novel and potentially druggable targets for effective targeted adjuvant therapy for ovarian cancer. The gene discussed is COX5B; the disease is ovarian carcinoma.