We decided to take this study a step further and investigate the relationship between tumor markers with pro- and anti-inflammatory cytokines (IL-6, tumor necrosis factor-α—TNF-α), as well as matrix metalloproteinases-2 and -9 (MMP-2, MMP-9), both of which have been shown to be essential in the tumor microenvironment. The gene discussed is MMP9; the disease is neoplasm.