It may downregulate Akt, mTOR, cyclin D1, vimentin, snail, slug, twist 1, zinc finger E-box-binding homeobox 1 (ZEB1), glycogen synthase kinase 3β (GSK3β) signaling, the NF-kB pathway, MMP-2, MMP-9, cortactin, membrane type 1-matrix metalloproteinase (MT1-MMP), c-Src kinase, and Bcl-2 and may upregulate p-21, Bax, E-cadherin, miR-205 in BC cells, leading to inhibition of cell proliferation, metastasis, and apoptotic cell death [38,107,108,109,110,111]. The gene discussed is AKT1; the disease is breast cancer.