Another study indicated that, in cancer patients who received carboplatin plus paclitaxel as chemotherapy, the NR1I2 rs1523130 (T > A, T > C, T > G) and rs1523127 (T > G) were related, with altered sensitivity to thrombocytopenia; as the A allele of rs1523130 and the G allele of rs1523127 exhibited a recessive and genotypic effect, the AA genotype of rs15233130 and the GG genotype of rs1523127 were correlated with a decreased sensitivity to thrombocytopenia. The gene discussed is NR1I2; the disease is cancer.