It has also been reported that the Cssmin of voriconazole, given to patients with hematological malignancies, is affected significantly by SNPs NR1I2 rs2461817 (A > C), rs7643645 (A > G), rs3732359 (G > A), rs3814057 (A > C) and rs6785049 (G > A) [82]. Here, NR1I2 is linked to hematologic disorder.