NR1I2 and non-small cell lung carcinoma: Also, homozygous for the mutant allele and heterozygous (CC + TC) Asian non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy with NR1I2 rs3814058 (T > C) exhibited higher risk of hematological toxicity than patients homozygous for the wild type allele (TT) [70].