In patients with T1DM only (group 2), sirtuin 1 was correlated with wave E, E/A’med, and A’med (R = −0.440, p = 0.040; R = 0.426, p = 0.048; R = −0.478, p = 0.024, respectively). This evidence concerns the gene SIRT1 and type 1 diabetes mellitus.