Additionally, SCCA2 and TARC serum levels increased with clinical severity as estimated by Objective Scoring Atopic Dermatitis (O-SCORAD), but SCCA2 was better at distinguishing clinical severity in paediatric AD (AUC; SCCA2: 0.929, TARC: 0.871) [73]. Here, SERPINB4 is linked to Alzheimer disease.