The number of studies and type of obesity evaluation were as follows: 2 studies evaluated the waist-to-hip ratio [57,61], 4 studies used the waist circumference (cm) [44,46,60,61], 3 studies used the plasma leptin level (ng/mL) [48,63,65] (in 2 of them, it was the exclusive obesity measurement [48,65]), 2 studies used the body fat percentage (%) [47,49,57], 1 study used the fat mass index (kg/m2) [47] as the level of adiposity, one study used the visceral adipose tissue (I) [43] and 1 study evaluated the visceral fat mass (g) and volume (cm3) as the exclusive obesity measurement [58]. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.