In the ovalbumin (OVA)-induced allergic rhinitis murine model, expression of TXNIP in nasal mucosa, MDA level, and SOD activity were measured, along with allergic rhinitis markers such as nasal symptoms of sneezing and nasal rubbing, OVA-specific IgE and histamine in serum, and OVA-specific IgE, IL-4, IL-5, and tumor necrosis factor (TNF)-α in the nasal lavage fluid. The gene discussed is IL4; the disease is allergic rhinitis.