Considering the wide range of protective and survival activities of Prdx6 [3,4,8,9,14,15,34,39,91,92,93,94,95,96,97], we chose to use the SCR (a model for cataract), which shows a spectrum of biochemical and morphological changes, including oxidative-induced cell biological changes during the progression of cataract [14,71,98,99,100]. The gene discussed is PRDX6; the disease is cataract.