PPARG and metabolic dysfunction-associated steatotic liver disease: As shown in Figure 1H, significant positive correlations were observed between Fasn transcript and C/EBPα and PPARγ proteins, indicating that increased C/EBPα and PPARγ by HFD were inhibited by G. cambogia, which regulated lipogenic genes such as Fasn. These results provide critical insight into the inhibitory effect of G. cambogia on NAFLD via suppressing hepatic steatosis.