We and others demonstrated that GLP-1 analogs like liraglutide and inhibitors of the enzyme dipeptidylpeptidase-4 (DPP-4), which rapidly degrades native GLP-1, ameliorate cardiovascular and thrombotic complications in animal models of lipopolysaccharide (LPS)-induced sepsis [9,10,11,12]. This evidence concerns the gene GCG and Sepsis.