We further examined the effect of the GLP-1 analog liraglutide on microvascular thrombosis and platelet reactivity in LPS-induced sepsis and observed less organ damage by thrombotic occlusion of the microvascular circulation in the lung, which might be secondary to improved endothelial function and bioavailability of nitric oxide (•NO) [12]. This evidence concerns the gene GCG and Sepsis.