By comparison with the AKI group, 4-HNE, NGAL, and HO-1 immunohistochemical score was significantly lower in all treated groups: AKI + APO (4-HNE, p < 0.01; NGAL, p < 0.01; HO-1, p < 0.001), AKI + HBO (4-HNE, p < 0.001; NGAL, p < 0.001; HO-1, p < 0.01) and AKI + APO + HBO (4-HNE, p < 0.01; NGAL, p < 0.05; HO-1, p < 0.001) (Figure 7). Here, LCN2 is linked to acute kidney injury.