NAF1 and pancreatic insulinoma: The rise in mLI, mROS, and cytosolic Ca2+ levels, upon NAF-1 depletion (Figure 5, Figure S3), and the finding that this rise could be suppressed by treatment with NAC and/or DFP (Figure 6), could suggest that NAF-1 deficiency in insulinoma cells triggers ferroptosis [49,50].