In HCC and CRC, CDR1as is considered oncogenic due to the sponging miR-7, which inhibits expression of the EGFR/RAF1/MAPK pathway, whereas, in glioma, it is potentially tumour-suppressive and the low expression levels were caused by interaction with miR-671-5p, resulting in increased tumour cell proliferation. The gene discussed is RAF1; the disease is neoplasm.