CKAP2L and cancer: Several proteins involved in cytoskeleton rearrangement such as actin, TNS3, KIF23, CKAP2L, NEDD9 and PLEC (Figure 3B and Table S2) were also hyperphosphorylated, indicating the known regulatory role of AXL in promoting cancer cell migration/invasion and inducing epithelial-mesenchymal transition (EMT) [15].