Finally, in NpT aside G3 tissue (n = 9), LOX-1 expression was detected again exclusively in the cytoplasm (NpT G3-nucleus vs NpT G3-cytoplasm: p < 0.001) (+) (Figure 3E), while the tumor counterpart lost the weak nuclear positivity found in G2 and consequently showed a strong positivity in the stroma (++), suggesting that this protein may acquire an extracellular localization, being released from tumor cells (Tumor G3-nucleus vs Tumor G3-extracellular space: p < 0.0001; Tumor G3-cytoplasm vs Tumor G3-extracellular space: p < 0.0001) (Figure 3F) (Table 2). This evidence concerns the gene OLR1 and neoplasm.