Therefore, we characterized the inflammatory infiltrated in WT and transgenic mice: the higher presence of CD3+ (pan T-cell), CD4+ (T-helper cell), and overall CD8+ (cytotoxic T lymphocytes) in PI3KγKD/KD and PI3Kγ−/− mice, where cancer lesions were less precocious and less numerous than in control mice, corresponds to what is reported in the literature. This evidence concerns the gene CD4 and cancer.