They are closely associated with the MPN driver oncogenes, such as BCR-ABL in chronic myeloid leukemia (CML) [2], JAK2V617F in polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF) [3,4], and calreticulin (CALR) frameshift mutations in ET and MF [5,6]. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.