Uckermann et al. [9] in their study on frozen tissue showed, similar to our work, a higher intensity for IDH-MUT glioma in peaks at 640 cm−1 (cysteine), 1174 cm−1 (proteins), 1337 cm−1 (lipids and proteins), suggesting a changed protein profile between the two molecular sub-groups. This evidence concerns the gene IDH1 and central nervous system cancer.