The modelling showed no stratification between PALB2 and BRCA2 carriers, which further confirmed that PALB2 was the partner and localizer of BRCA2. As shown in Figure 4, BRCA1/2 carriers were more likely to have family history of ovarian cancer, but this was not seen in the PALB2 families. The gene discussed is BRCA2; the disease is ovarian cancer.