In an effort to identify potential biomarkers for stomach cancer cells’ response to chemopotentiation by LDFRT, we recently identified DUOX2, an enzyme involved in hydrogen peroxide (H2O2) production, as an important mediator of hyper-radiosensitivity (HRS) and contributor to chemopotentiation by LDFRT in these cells [18]. Here, DUOX2 is linked to gastric neoplasm.