INS and cancer: For example, narigenin, a grapefruit flavone, inhibits basal and insulin-stimulated glucose uptake, causing inhibition of proliferation of cancer cells, resveratrol decreases the expression of GLUT1 in cancer, hespertin downregulates GLUT1 and impairs translocation of GLUT4 from an intracellular compartment into a plasma membrane, kaempferol decreases the expression of GLUT1, and so on [73].