H1993 cells bearing a MET amplification, which is recognized as one of the molecular mechanisms of EGFR-mutant NSCLC resistance to EGFR-TKIs, were >5-fold more resistant to docetaxel than were A549, H2228, and H3122 cells, which were exquisitely responsive (Figure S2A). The gene discussed is MET; the disease is non-small cell lung carcinoma.