Additionally, DJ-1 mRNA and DJ-1 protein increased in TNM stage II, III, and IV colorectal cancer tumor tissues but not TNM stage I. SW620 is a metastasis-derived human colorectal adenocarcinoma cell; SW620 shows higher tumorigenic and metastatic than SW480 cells [40]. The gene discussed is PARK7; the disease is colorectal adenocarcinoma.